Answer
Jesus was referred to as āJesus of Nazarethā for several reasons. For one thing, in Bible times people were often identified by their native area or place of residence. The man who carried Jesusā cross when He was no longer able to, for example, was called Simon of Cyrene, noting his name and his place of residence (Luke 23:26). This distinguishes him from all other Simons and from all other residents of Cyrene who were not named Simon. Although Bethlehem was the place of Jesusā birth, Nazareth was the place where Jesus had lived until He began His public ministry, and therefore He is said to be āof Nazareth.ā
Matthew 2:23 tells us that Joseph settled his family in Nazarethāafter returning from Egypt where he had fled to protect Jesus from Herodāin order to fulfill āwhat was said through the prophets: āHe will be called a Nazarene.āā The words here are not found in any of the books of the Old Testament, and there has been much difficulty in ascertaining the meaning of this passage. Most commentators agree that the prophecies respecting the coming Messiah were that He was to be of humble origin and would be despised and rejected (Isaiah 53; Psalm 22) and that the phrase āhe shall be calledā means the same as āHe shall be.ā When Matthew says, therefore, that the prophecies were āfulfilled,ā his meaning is that the predictions of the prophets that the Messiah would be of a low and despised condition and would be rejected, were fully accomplished in His being an inhabitant of Nazareth.
The phrase āJesus of Nazarethā is first used in the Bible by Phillip who, after being called by Jesus to follow Him, told Nathanael, "We have found him of whom Moses in the Law and also the prophets wrote, Jesus of Nazareth, the son of Joseph" (John 1:45). By calling Him Jesus of Nazareth, Phillip may also have been making a statement about the lowliness of His birth. The character of the people of Nazareth was such that they were despised and condemned. Nathanaelās response, āCan anything good come from Nazareth?ā (John 1:46) would seem to indicate such. To come from Nazareth, therefore, or to be a Nazarene, was the same as to be despised, or to be esteemed of low birth. The Messiah who would come to save His people would be āa root out of dry ground, having no form or comelinessā (Isaiah 53:2). He would be ādespised and rejected of menā from whom men hid their faces and āesteemed him notā (Isaiah 53:3).
Jesus of Nazareth was born and grew up in humble circumstances, but His impact on the world has been greater than anyone ever born before or since. He came to āsave His people from their sinsā (Matthew 1:21), a feat that could be accomplished by none other than God incarnate.